试管婴儿前为何要筛查染色体?

发布时间:2016-08-08 11:15:34 阅读量:31,867

做试管婴儿手术之前夫妻双方都需要做全面的检查,这是保障试管婴儿手术顺利进行的关键,以达到试管婴儿优生优育目的。试管婴儿前的检查能够提前得知夫妻双方是否患病,便于进行及时正确的治疗,以免影响试管婴儿的治疗周期。试管婴儿术前会要求做染色体检查,这又是为什么呢?相信有很多人都很好奇!

首先,做试管婴儿的人群中,很多都是高龄女性,而高龄女性怀孕有一定风险,因体内卵子中染色体异常率高,会导致不孕不育。因此,对于高龄女性做试管婴儿,在实行试管手术之前都需要进行女性染色体检查方可进行手术。

其次,有些做试管婴儿的夫妻本来就是因为存在染色体病的,因此,在试管婴儿手术前也必须进行染色体检查,一方面确定存在问题的是哪对染色体,以便确定试管婴儿治疗技术;另一方面就是检查是否存在其他异常的染色体,以确保试管婴儿技术能够正常进行。

其实,不仅在试管婴儿收拾之前要做染色仪检查,在胚胎移植之前也会做染色体检查,这么做是为了检测妇女卵细胞中携带人类遗传密码的染色体的缺陷。卵细胞染色体数目错误可能会导致胚胎流产,或导致唐氏综合征之类的严重婴儿病症。年轻妇女多达一半的卵细胞以及年届39岁以上妇女75%的卵细胞会有染色体异常现象。在胚胎植入子宫前对其进行染色体分析,只移植染色体正常的胚胎,能够有效提高试管婴儿的成功率,降低流产率,帮助遗传高风险的家庭生育健康的宝宝,避免出生遗传异常婴儿,降低人群中出生缺陷。但是,在胚胎移植前做染色体检测只有在做第三代试管婴儿时才会采用,其他一二代试管婴儿通常不会进行检测。

第三代试管婴儿技术又称胚胎植入前遗传学诊断(PGD)技术,它可以在胚胎移植前进行遗传学诊断,挑选出健康的胚胎进行移植,淘汰不健康的胚胎,以达到优生优育的目的。这种技术尤其是对患有染色体病的、不明原因不孕、习惯性流产的不孕不育患者更为有效。当然,该技术在国外还通常被用来挑选胚胎性别。很多人去泰国选性别、做龙凤胎就是利用该技术。

泰国试管婴儿孟顾问

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