抗精子抗体可以做试管婴儿吗?

发布时间:2016-08-03 14:02:55 阅读量:12,638

在试管婴儿临床治疗中,不免会出现很多因各种因素导致不孕不育的患者。其中就有免疫性不孕的患者,导致免疫性不孕的病因之一就是男性或女性体内存在抗精子抗体。那么,抗精子抗体对做试管婴儿有影响吗?

我们知道,正常的受孕过程是精子游过酸性的阴道“池”,宫颈的“泥水河”,穿越过宫腔的“大草原”,才能进入输卵管,与卵子结合形成受精卵,最后经由输卵管把受精卵输送到子宫腔着床、继而发育成胎儿。当有抗精子抗体时,精子周围会粘附大量抗体,甚至凝聚成团。如果当一群精子“捆绑”在一起,带着沉重的“行李”向前运动,那么精子如何能穿越重重障碍与卵子相会呢?

另外,有些人抗精子抗体的滴度不高,所以表面看精子凝集现象并不严重,精子活动率也不低,可实际上在精子表面已包裹上一层抗精子抗体,妨碍了精子与卵子结合,从而造成男性不育的发生。

♥为什么会出现抗精子抗体的情况?♥
因精子进入到女性体内,对她们来说显然是一种异物,但是,不是所有精子都会引起女性机体产生免疫反映,只有进入血液的精子刺激到致敏淋巴细胞,才会触发女性的免疫系统,所以正常的女性体内不会产生抗精子抗体。如果在某种情况下,由于女性生殖道的炎症和损伤(如阴道炎、输卵管炎、子宫内膜炎等生殖系统炎症)、经期、产后恶露未净、生殖器官异常出血时性交等。如果在此种状态下性生活,精子、精液很容易与女性的血液接触,进而“激发”女性免疫系统产生抗体,在女性血清和宫颈粘液中会产生抗体。

♥抗精子抗体能做试管婴儿吗?影响大不?♥
试管婴儿技术是把卵子取出体外,胚胎学家们会在实验室将精液特殊处理,在培养皿中将精子和卵子共培养,使卵子受精,并把受精卵培养至第三或五天,最后移植到女性子宫腔内。

由此我们可以看出,在试管婴儿的助孕过程中,精液会被特殊处理—洗涤,极大的去除了体液中的抗精子抗体。在体外就完成了受精,形成胚胎进入女性体内,而不是精子。因此,即便是男性和女性的体内同时存在抗精子抗体,也不会影响到试管婴儿成功率,只要女性子宫内膜厚度正常、血运丰富,就可以受孕啦。

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